Disease Penetrance of Late-Onset Parkinsonism
نویسندگان
چکیده
منابع مشابه
Disease penetrance of late-onset parkinsonism: a meta-analysis.
IMPORTANCE Mutations in SNCA, LRRK2, VPS35, EIF4G1, and DNAJC13 have been implicated in late-onset familial parkinsonism. However, the estimated disease penetrance of these mutations varies widely. OBJECTIVE To compare penetrance of various mutations reported in published genetic studies to improve the understanding of late-onset parkinsonism. DATA SOURCES Forty-nine previously published st...
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1 Department of Biomedical Sciences and Biotechnologies, University of Brescia and National Institute of Neuroscience, 25123 Brescia, Italy 2 National Research Council, Institute of Neuroscience, 09124 Cagliari, Italy 3 Department of Biomedical Science and National Institute of Neuroscience, University of Cagliari, 09124 Cagliari, Italy 4 Department of Neurological, Neuropsychological, Morpholo...
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ژورنال
عنوان ژورنال: JAMA Neurology
سال: 2014
ISSN: 2168-6149
DOI: 10.1001/jamaneurol.2014.1909